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What are SARMs? Selective Androgen Receptor Modulators = SARMs. Androgens are hormones that act as molecules or ions to bind to the cellular androgen receptors and the receptors are involved in transmitting complex signals that result in greater expressions of specific genes. When bodybuilders, athletes, or people with muscle wasting diseases ranging from cancer to osteoporosis partake in anabolic steroids to increase their muscles, the binding of androgen hormones to the androgen receptor is what results in more muscle and decreased body fat. Drugs and substances that block or stimulate the androgen receptor are called “selective receptor modulators”.
YK11 is a rate compound that was first studied by researcher Yuichiro Kanno of Toho University in 2011. Initial studies confirmed that the compound is in fact a SARM. YK11 attaches to the androgen receptor. Kanno’s published report of the results from this study exposed that muscle cells exposed to YK11 create more anabolic effects at 500 nanomoles than when exposed to DHT and other similar compounds at the same amount.
Chemical Composition of YK11
Research Chemical: YK-11
YK-11 is researched heavily in Japan by researchers and chemists determined to find out what the potential benefits of the SARM may be for future human use in pharmaceutical products. Initial studies have discovered that YK11 is a potent SARM in terms of creating anabolic effects in the body that lead to muscle enhancement while inhibiting myostatin effects. The potential for YK11 to be used in the treatment of diseases causing muscle waste is something researchers are considering further.
YK11 is Similar to Testosterone
Testosterone is an androgen, naturally occurring steroid hormone in the body. Medically, it can be used to treat breast cancer or treat male hypogonadism. Athletes and bodybuilders sometimes use it illegally to increase athletic ability. Steroids can cause undesirable side effects including changes in sexual function, sleep disturbances, increased body fat, reduced muscle bulk and strength, and decreased self-confidence and motivation.
Most SARMs have limited androgenic side effects, but often have several anabolic effects similar to that of testosterone. YK11 causes muscle cells to create more of the protein follistatin, a myostatin inhibitor. Myostatin is a protein that limits the growth and production of muscle tissues. Inhibiting myostatin improves the body’s ability to create leaner and bigger muscle tissue. Follistatin is expressed in nearly all tissues of animals. Follistatin is currently under examination for its role in regulating muscle grown in mice. While YK11 appears to increase muscle mass similar to testosterone, according to the Biological and Pharmaceutical Bulletin published in 2013, YK11 doesn’t have the detrimental side effects commonly experienced with testosterone, but in studies with lab animals it was shown to be as good as testosterone in terms of muscle building and strengthening. Studies show YK11 side effects to involve body hair growth and enhanced aggression.
YK11 Research Results
In lab studies, YK-11 has been shown to:
- Increase muscle mass and strength
- Inhibit myostatin
- Have minimal side effects
Where to Buy YK11
If you are a researcher or chemist and would like to conduct your own studies using the SARM YK11, you’ll want to know where you can buy it. The internet is the easiest place to order research chemicals including YK11. Peptides Warehouse offers YK11 and a combo pack of YK11 and Rad 140, another research chemical at affordable prices. Peptides Warehouse is a trusted provider of research chemicals and peptides and partners with manufacturers of a wide variety of research peptides made in the USA in order to provide the highest quality SARMS and peptides available at the lowest prices for your research needs.